Laboratory for Biotronic Engineering 

Journal Papers

  1. L. Guo, M. Ma, N. Zhang, R. Langer, and D. G. Anderson, Stretchable Polymeric Multielectrode Array for Conformal Neural Interfacing, Advanced Materials, vol. 26, no. 9, pp. 1427–1433, March 2014. [PDF] [SUP MAT] [Inside Front Cover]

  2. M. Ma, L. Guo, D. G. Anderson, and R. Langer, Bio-Inspired Polymer Composite Actuator and Generator Driven by Water Gradients, Science, vol. 339, no. 6116, pp. 186–189, January 2013. [ONLINE] [PDF] [SUP MAT] [VIDEO1] [VIDEO2] [Selected as Issue Highlights by Science Editors. Featured in a perspective paper (Science, 2013, 339, 150-151). Selected as "Best of 2013" by MIT]
    Media Reports: Science, MIT News, C&EN, Boston Globe, NBC News, physicsworld.com, Science Recorder, TechNewsDaily, Txchnologist, Smithsonian.com, DVICE, Ars Technica, Newscientist, ScienceDaily, gizmag, Knovel, Electronic Products

  3. L. Guo, G. S. Guvanasen, X. Liu, C. Tuthill, T. R. Nichols, and S. P. DeWeerth, A PDMS-Based Integrated Stretchable Microelectrode Array (isMEA) for Neural and Muscular Surface Interfacing, IEEE Transactions on Biomedical Circuits and Systems, vol. 7, no. 1, pp. 1–10, February 2013. [PDF]

  4. K. W. Meacham, L. Guo, S. P. DeWeerth, and S. Hochman, Selective Stimulation of the Spinal Cord Surface Using a Stretchable Microelectrode Array, Frontiers in Neuroengineering, vol. 4, article 5, April 2011. [PDF]

  5. L. Guo and S. P. DeWeerth, An Effective Lift-Off Method for Patterning High-Density Gold Interconnects on an Elastomeric Substrate, Small, vol. 6, no. 24, pp. 2847–2852, December 2010. [PDF] [SUP MAT]

  6. L. Guo and S. P. DeWeerth, High-Density Stretchable Electronics: Toward an Integrated Multilayer Composite, Advanced Materials, vol. 22, no. 36, pp. 4030–4033, September 2010. [PDF]

  7. L. Guo, K. W. Meacham, S. Hochman, and S. P. DeWeerth, A PDMS-Based Conical-Well Microelectrode Array for Surface Stimulation and Recording of Neural Tissues, IEEE Transactions on Biomedical Engineering, vol. 57, no. 10, pp. 2485–2494, October 2010. [PDF]

  8. S. A. Desai, J. D. Rolston, L. Guo, and S. M. Potter, Improving Impedance of Implantable Microwire Multi-Electrode Arrays by Ultrasonic Electroplating of Durable Platinum Black, Frontiers in Neuroengineering, vol. 3, article 5, May 2010. [PDF]

  9. K. W. Meacham, R. J. Giuly, L. Guo, S. Hochman, and S. P. DeWeerth, A Lithographically-Patterned, Elastic Multi-Electrode Array for Surface Stimulation of the Spinal Cord, Biomedical Microdevices, vol. 10, no. 2, pp. 259–269, April 2008. [PDF]


Refereed Conference Papers

  1. G. S. Guvanasen, R. J. Aguilar, L. Guo, C. Karnati, S. Rajaraman, T. R. Nichols, and S. P. DeWeerth, Development of a Stretchable, Penetrating Electrode Array for Measuring Intramuscular Electromyographic Activity, The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Freiburg, Germany, October 27-31, 2013. [PDF]

  2. A. Srinivasan, L. Guo, and R. V. Bellamkonda, Regenerative Microchannel Electrode Array for Peripheral Nerve Interfacing, talk, The 5th International IEEE EMBS Conference on Neural Engineering, Cancun, Mexico, April 27-May 1, 2011. [PDF]

  3. L. Guo, G. S. Guvanasen, C. Tuthill, T. R. Nichols, and S. P. DeWeerth, A Low-Cost, Easy-Fabricating Stretchable Microneedle-Electrode Array for Intramuscular Recording and Stimulation, The 5th International IEEE EMBS Conference on Neural Engineering, Cancun, Mexico, April 27-May 1, 2011. [PDF]

  4. L. Guo, G. S. Guvanasen, C. Tuthill, T. R. Nichols, and S. P. DeWeerth, Characterization of a Stretchable Multielectrode Array for Epimysial Recording, talk, The 5th International IEEE EMBS Conference on Neural Engineering, Cancun, Mexico, April 27-May 1, 2011. [PDF]

  5. L. Guo, I. P. Clements, R. V. Bellamkonda, and S. P. DeWeerth, A Conformable Microelectrode Array (cMEA) with Integrated Electronics for Interfacing to a Regenerated Peripheral Nerve, talk, IEEE Biomedical Circuits and Systems Conference 2010, Paphos, Cyprus, November 3-5, 2010. [Selected as one of the highlights] [PDF]

  6. S. P. DeWeerth, A. C. Hughes, K. Sundar, L. Guo, and L. H. Ting, A Hybrid Muscle-in-the-Loop Robot System for Studying the Neuromechanical Properties of Movement, talk, The 3rd IEEE RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics, Tokyo, Japan, September 26-29, 2010. [PDF]

  7. A. C. Hughes, L. Guo, and S. P. DeWeerth, Interleaved Multichannel Epimysial Stimulation for Eliciting Smooth Contraction of Muscle with Reduced Fatigue, talk, The 32st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Buenos Aires, Argentina, August 31-September 4, 2010. [PDF]

  8. L. Guo, L. J. Kitashima, C. R. Villari, A. M. Klein, and S. P. DeWeerth, Muscle Surface Recording and Stimulation Using Integrated PDMS-Based Microelectrode Arrays: Recording-Triggered Stimulation for Prosthetic Purposes, talk, IEEE Biomedical Circuits and Systems Conference 2009, Beijing, China, November 26-28, 2009. [PDF]

  9. L. Guo and S. P. DeWeerth, Implementation of Integratable PDMS-Based Conformable Microelectrode Arrays Using a Multilayer Wiring Interconnect Technology, The 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Minneapolis, Minnesota, September 2-6, 2009. [PDF]

  10. L. Guo and S. P. DeWeerth, PDMS-Based Conformable Microelectrode Arrays with Selectable Novel 3-D Microelectrode Geometries for Surface Stimulation and Recording, The 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Minneapolis, Minnesota, September 2-6, 2009. [PDF]

  11. W. Jia, X. Liu, X. Gao, L. Guo, Y. Lei, Y. Ku, and S. Gao, The Detection of Seizure Vulnerable Period from Epidural EEG Recordings of Epilepsy Rat, The 2nd International IEEE EMBS Conference on Neural Engineering, Washington D.C., March 16-19, 2005.


Patents

  1. M. Ma, L. Guo, D. G. Anderson, O. C. Farokhzad, and R. S. Langer, A Bio-inspired Polymer Composite Actuator Driven by Water Gradient and Methods of Making the Same, PCT and U.S. Patent Pending, US 14071482.

  2. G. S. Guvanasen, S. Rajaraman, L. Guo, T. R. Nichols, and S. P. DeWeerth, 3D Microelectrode Device for Live Tissue Applications, U.S. Patent Pending.

  3. A. Srinivasan, L. Guo, Y. Choi, and R. V. Bellamkonda, Regenerative Microchannel Electrode Array for Peripheral Nerve Interfacing, WO 2012139124.

  4. L. Guo and S. P. DeWeerth, Integrated Method for High-Density Interconnection of Electronic Components through Stretchable Interconnects, US 8349727 B2.