Laboratory for Biotronic Engineering @ OSU 

Publications

2016

  • L. Guo*, The Pursuit of Chronically Reliable Neural Interfaces, Frontiers in Neuroscience, in press.

  • G. S. Guvanasen, L. Guo, R. J. Aguilar, A. L. Cheek, C. S. Shafor, S. Rajaraman, T. R. Nichols, and S. P. DeWeerth, A Stretchable Microneedle Electrode Array for Stimulating and Measuring Intramuscular Electromyographic Activity, IEEE Transactions on Neural Systems and Rehabilitation Engineering, in press.

  • L. Guo*, Conducting Polymers as Smart Materials for Tissue Engineering, Fundamental Principles of Smart Materials for Tissue Engineering (RSC Smart Materials Series), Chapter 9, Royal Society of Chemistry, in press.

  • Y. Wang, B. Yan, Y. Wu, and L. Guo*, Hydrogel-Reinforced Polypyrrole Electroactuator, The 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Orlando, Florida, August 16-20, 2016.

  • Y. Gao, A. Wilford, L. Guo, Self-correcting Multi-atlas Segmentation, Proc. SPIE 9784, Medical Imaging 2016: Image Processing, 97842Q, March 21, 2016. [LINK]

  • Y. Wang and L. Guo*, Nanomaterial-Enabled Neural Stimulation, Frontiers in Neuroscience, vol. 10, article 69, March 2016. [LINK] [PDF]

2015

  • B. Yan, B. Li, F. Kunecke, Z. Gu, and L. Guo*, Polypyrrole-Based Implantable Electroactive Pump for Controlled Drug Microinjection, ACS Applied Materials & Interfaces, vol. 7, no. 27, pp. 14563–14568, July 2015. [LINK] [SUP MAT]

  • L. Guo*, Stretchable Polymeric Neural Electrode Array: Toward a Reliable Neural Interface, Materials Research Society 2015 Spring Meeting, San Francisco, California, April 6–10, 2015. [LINK] [Invited]

2014

  • L. Guo, M. Ma, N. Zhang, R. Langer, and D. G. Anderson, Stretchable Polymeric Multielectrode Array for Conformal Neural Interfacing, Advanced Materials, vol. 26, no. 9, pp. 1427–1433, March 2014. [PDF] [SUP MAT] [Inside Front Cover]

2013

2011

  • A. Srinivasan, L. Guo, and R. V. Bellamkonda, Regenerative Microchannel Electrode Array for Peripheral Nerve Interfacing, The 5th International IEEE EMBS Conference on Neural Engineering, Cancun, Mexico, April 27-May 1, 2011. [PDF]

  • L. Guo, G. S. Guvanasen, C. Tuthill, T. R. Nichols, and S. P. DeWeerth, A Low-Cost, Easy-Fabricating Stretchable Microneedle-Electrode Array for Intramuscular Recording and Stimulation, The 5th International IEEE EMBS Conference on Neural Engineering, Cancun, Mexico, April 27-May 1, 2011. [PDF]

  • L. Guo, G. S. Guvanasen, C. Tuthill, T. R. Nichols, and S. P. DeWeerth, Characterization of a Stretchable Multielectrode Array for Epimysial Recording, talk, The 5th International IEEE EMBS Conference on Neural Engineering, Cancun, Mexico, April 27-May 1, 2011. [PDF]

  • K. W. Meacham, L. Guo, S. P. DeWeerth, and S. Hochman, Selective Stimulation of the Spinal Cord Surface Using a Stretchable Microelectrode Array, Frontiers in Neuroengineering, vol. 4, article 5, April 2011. [PDF]

2010

  • L. Guo and S. P. DeWeerth, An Effective Lift-Off Method for Patterning High-Density Gold Interconnects on an Elastomeric Substrate, Small, vol. 6, no. 24, pp. 2847–2852, December 2010. [PDF] [SUP MAT]

  • L. Guo, I. P. Clements, R. V. Bellamkonda, and S. P. DeWeerth, A Conformable Microelectrode Array (cMEA) with Integrated Electronics for Interfacing to a Regenerated Peripheral Nerve, IEEE Biomedical Circuits and Systems Conference 2010, Paphos, Cyprus, November 3-5, 2010. [Selected as one of the highlights] [PDF]

  • L. Guo, K. W. Meacham, S. Hochman, and S. P. DeWeerth, A PDMS-Based Conical-Well Microelectrode Array for Surface Stimulation and Recording of Neural Tissues, IEEE Transactions on Biomedical Engineering, vol. 57, no. 10, pp. 2485–2494, October 2010. [PDF]

  • S. P. DeWeerth, A. C. Hughes, K. Sundar, L. Guo, and L. H. Ting, A Hybrid Muscle-in-the-Loop Robot System for Studying the Neuromechanical Properties of Movement, talk, The 3rd IEEE RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics, Tokyo, Japan, September 26-29, 2010. [PDF]

  • L. Guo and S. P. DeWeerth, High-Density Stretchable Electronics: Toward an Integrated Multilayer Composite, Advanced Materials, vol. 22, no. 36, pp. 4030–4033, September 2010. [PDF]

  • A. C. Hughes, L. Guo, and S. P. DeWeerth, Interleaved Multichannel Epimysial Stimulation for Eliciting Smooth Contraction of Muscle with Reduced Fatigue, talk, The 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Buenos Aires, Argentina, August 31-September 4, 2010. [PDF]

  • S. A. Desai, J. D. Rolston, L. Guo, and S. M. Potter, Improving Impedance of Implantable Microwire Multi-Electrode Arrays by Ultrasonic Electroplating of Durable Platinum Black, Frontiers in Neuroengineering, vol. 3, article 5, May 2010. [PDF]

2009

  • L. Guo, L. J. Kitashima, C. R. Villari, A. M. Klein, and S. P. DeWeerth, Muscle Surface Recording and Stimulation Using Integrated PDMS-Based Microelectrode Arrays: Recording-Triggered Stimulation for Prosthetic Purposes, IEEE Biomedical Circuits and Systems Conference 2009, Beijing, China, November 26-28, 2009. [PDF]

  • L. Guo and S. P. DeWeerth, Implementation of Integratable PDMS-Based Conformable Microelectrode Arrays Using a Multilayer Wiring Interconnect Technology, The 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Minneapolis, Minnesota, September 2-6, 2009. [PDF]

  • L. Guo and S. P. DeWeerth, PDMS-Based Conformable Microelectrode Arrays with Selectable Novel 3-D Microelectrode Geometries for Surface Stimulation and Recording, The 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Minneapolis, Minnesota, September 2-6, 2009. [PDF]

2008

  • K. W. Meacham, R. J. Giuly, L. Guo, S. Hochman, and S. P. DeWeerth, A Lithographically-Patterned, Elastic Multi-Electrode Array for Surface Stimulation of the Spinal Cord, Biomedical Microdevices, vol. 10, no. 2, pp. 259–269, April 2008. [PDF]

2005

  • W. Jia, X. Liu, X. Gao, L. Guo, Y. Lei, Y. Ku, and S. Gao, The Detection of Seizure Vulnerable Period from Epidural EEG Recordings of Epilepsy Rat, The 2nd International IEEE EMBS Conference on Neural Engineering, Washington D.C., March 16-19, 2005.


Patents

  • A. Srinivasan, L. Guo, Y. Choi, and R. V. Bellamkonda, Regenerative Microchannel Electrode Array for Peripheral Nerve Interfacing, PCT/US 2012032784.

  • G. S. Guvanasen, S. Rajaraman, R. Aguilar, Jr., L. Guo, T. R. Nichols, and S. P. DeWeerth, 3D Microelectrode Device for Live Tissue Applications, US 9248273.

  • M. Ma, L. Guo, D. G. Anderson, O. C. Farokhzad, and R. S. Langer, A Bio-inspired Polymer Composite Actuator Driven by Water Gradient and Methods of Making the Same, US 9236556.

  • L. Guo and S. P. DeWeerth, Integrated Method for High-Density Interconnection of Electronic Components through Stretchable Interconnects, US 8349727.